Alternative and complementary therapies used in renal patients: review of the literature
DOI:
https://doi.org/10.24054/cbs.v3i2.4048Keywords:
Kidney disease, alternative therapies, complementary therapies, complementary medicineAbstract
Objective: To describe complementary and alternative therapies reported in patients with kidney disease and the effects found. Material and methods: A bibliographic search was performed in several databases: PubMed, Web of Science, RedAlyC, Scielo, Cochrane Library, and Scopus data, Medline, Embase, and EBSCO, using keywords to locate articles from the last 10 years in English and Spanish. Therapies were classified into 5 groups: complete medical systems, mind-body medicine, biological therapies, manipulative and body-based practices, and energy therapies, by means of matrices. Results: 13 articles were found in total of alternative or complementary therapies used in patients with kidney disease: 3 in medical systems, 2 in mind-body medicine, 4 in biological therapies, and 4 in manipulation-based practices and body and energy therapies. Conclusions: Of the 13 articles found 9 of them showed positive effects in the direct treatment of patients' kidney disease or symptoms, however, the groups of studies were too small to point out that these treatments really work. We found 4 articles focused not on the direct treatment of the disease or its symptoms but on the psychoemotional improvement of the patients, in which they found that the use of alternative therapies in conjunction with their treatments helped to reduce stress and anxiety.
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Argaiz, E. R., Morales-Juárez, L., Razo, C., Ong, L., Rafferty, Q., Rincón-Pedrero, R., Vélez-Ruíz, J. O., & Chertow, G. M. (2023). La carga de enfermedad renal crónica en México. Análisis de datos basado en el estudio Global Burden of Disease 2021. Gaceta Médica de México, 159(6), 501-508. https://doi.org/10.24875/gmm.23000393
Bello, A. K., Levin, A., Lunney, M., Osman, M. A., Ye, F., Ashuntantang, G., Ethical, J., Rathi, M., Cooper, B. A., & Tonelli, M. (2019). Global Kidney Health Atlas: A report by the International Society of Nephrology on the Global Burden of End-stage Kidney Disease and Capacity for Kidney Replacement Therapy and Conservative Care across World Countries and Regions. International Society of Nephrology. https://www.theisn.org/wp-content/uploads/2021/05/GKHAtlas_2019_WebFIle-1.pdf
Ben Salah, G., Farooqui, M., Salem Alshammari, M., Elghazali, A., Kassem, L., Ibrahim, N., Alshehri, H., & Arshad, M. M. (2023). Prevalence, types and disclosure of complementary and alternative medicine (CAM) use among chronic kidney disease (CKD) patients in Saudi Arabia. Journal of Pharmaceutical Policy and Practice, 16(1), Article 30. https://doi.org/10.1186/s40545-023-00589-2
Bennett, P. N., Parsons, T., Ben-Moshe, R., Neal, M., Weinberg, M. K., Gilbert, K., Rawson, H., Ockerby, C., Finlay, P., & Hutchinson, A. (2015). Intradialytic Laughter Yoga therapy for haemodialysis patients: a pre-post intervention feasibility study. BMC Complementary and Alternative Medicine, 15(1). https://pubmed.ncbi.nlm.nih.gov/26055513/
Bikbov, B., Purcell, C. A., Levey, A. S., Smith, M., Abdoli, A., Abebe, M., Adebayo, O. M., Afarideh, M., Agarwal, S. K., Agudelo-Botero, M., Ahmadian, E., Al-Aly, Z., Alipour, V., Almasi-Hashiani, A., Al-Raddadi, R. M., Alvis-Guzman, N., Amini, S., Andrei, T., Andrei, C. L., ... Murray, C. J. L. (2020). Global, regional, and national burden of chronic kidney disease, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017. The Lancet, 395(10225), 709–733. https://linkinghub.elsevier.com/retrieve/pii/S0140673620300453
Bullen, A., Awdishu, L., Lester, W., Moore, T., & Trzebinska, D. (2018). Effect of acupuncture or massage on health-related quality of life of hemodialysis patients. The Journal of Alternative and Complementary Medicine, 24(11), 1069–1075. https://pubmed.ncbi.nlm.nih.gov/29851511/
Claure-Del Granado, R., & Espinosa-Cuevas, M. (2021). Herbal nephropathy. Contributions to Nephrology, 199, 143–154. https://doi.org/10.1159/000517693
Colson, C. R. D., & De Broe, M. E. (2005). Kidney injury from alternative medicines. Advances in Chronic Kidney Disease, 12(3), 261–275. https://doi.org/10.1016/j.ackd.2005.03.006
Geller, A. I., Shehab, N., Weidle, N. J., Lovegrove, M. C., Wolpert, B. J., Timbo, B. B., Mozersky, R. P., & Budnitz, D. S. (2015). Emergency department visits for adverse events related to dietary supplements. New England Journal of Medicine, 373(16), 1531–1540. https://doi.org/10.1056/nejmsa1504267
Granado, R. C., & Chávez-Íñiguez, J. (2024). Herbal and Dietary Supplements: Hidden Dangers to Kidney Health. Kidney News, 16(8), 22-23. https://www.kidneynews.org/view/journals/kidney-news/16/8/article-p22_12.xml
Grubbs, V., Plantinga, L. C., Tuot, D. S., Hedgeman, E., Saran, R., Saydah, S., Rolka, D., & Powe, N. R. (2013). Americans' use of dietary supplements that are potentially harmful in CKD. American Journal of Kidney Diseases, 61(5), 739–747. https://linkinghub.elsevier.com/retrieve/pii/S0272638613000176
Instituto Nacional de Estadística y Geografía. (n.d.). Instituto Nacional de Estadística y Geografía (INEGI). Retrieved January 1, 2025, from https://www.inegi.org.mx/
Instituto Nacional del Cáncer. (2015). Medicina complementaria y alternativa. https://www.cancer.gov/espanol/cancer/tratamiento/mca
Isnard Bagnis, C., Deray, G., Baumelou, A., Le Quintrec, M., & Vanherweghem, J. L. (2004). Herbs and the kidney. American Journal of Kidney Diseases, 44(1), 1–11. https://doi.org/10.1053/j.ajkd.2004.02.009
Jha, V. (2010). Herbal medicines and chronic kidney disease. Nephrology, 15(s2), 10–17. https://doi.org/10.1111/j.1440-1797.2010.01305.x
Karadag, E., & Samancioglu Baglama, S. (2019). The effect of aromatherapy on fatigue and anxiety in patients undergoing hemodialysis treatment: A randomized controlled study. Holistic Nursing Practice, 33(4), 222–229. https://pubmed.ncbi.nlm.nih.gov/31192834/
Kefale, B., Alebachew, M., Tadesse, Y., & Engidawork, E. (2019). Quality of life and its predictors among patients with chronic kidney disease: A hospital-based cross sectional study. PLOS ONE, 14(2), Article e0212184. https://doi.org/10.1371/journal.pone.0212184
Kurani, S., Hickson, L. J., Thorsteinsdottir, B., Barreto, E. F., Haag, J. D., Shah, N. D., Williams, A. W., & Inselman, J. W. (2019). Supplement use by US adults with CKD: A population-based study. American Journal of Kidney Diseases, 74(6), 862–865. https://linkinghub.elsevier.com/retrieve/pii/S0272638619307711
Li, B., Cairns, J. A., Draper, H., Dudley, C., Forsythe, J. L., Johnson, R. J., Metcalfe, W., Tomson, C. R., Watson, C. J. E., & Roderick, P. J. (2017). Estimating health-state utility values in kidney transplant recipients and waiting-list patients using the EQ-5D-5L. Value in Health, 20(7), 976–984. https://linkinghub.elsevier.com/retrieve/pii/S1098301516300237
Liu, J.-Y., Chen, X.-X., Tang, S. C.-W., Lao, L.-X., Sze, S. C.-W., Lee, K.-F., Zhang, K. Y.-B., Chen, C. Y.-C., & Fong, W.-F. (2015). Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy. Journal of Functional Foods, 14, 12–22. https://doi.org/10.1016/j.jff.2015.01.034
Liu, S., Li, X., Li, H., Liang, Q., Chen, J., & Chen, J. (2015). Comparison of tripterygium wilfordii multiglycosides and tacrolimus in the treatment of idiopathic membranous nephropathy: a prospective cohort study. BMC Nephrology, 16(1). https://pubmed.ncbi.nlm.nih.gov/26637482/
Manjiri, M. A., Asadpour, A. A., Yousefi, M., Jamali, J., Davachi, B., Ahmadpour, M. R., Rakhshanderou, S., & Avan, A. (2023). The effects of Cynodon dactylon (Poaceae family) and Dolichos biflorus (Fabaceae family) extracts on decreasing size and excretion of kidney and urinary tract stones: a randomized, double-blind controlled trial. Journal of Complementary and Integrative Medicine, 20(1), 214–222. https://pubmed.ncbi.nlm.nih.gov/35938937/
Millstine, D. (n.d.). Tipos de medicina alternativa y complementaria. Manual MSD versión para público general. Retrieved January 28, 2024, from https://www.msdmanuals.com/es-mx/hogar/temas-especiales/medicina-alternativa-complementaria-e-integrativa/tipos-de-medicina-alternativa-y-complementaria
Mishra, A., Bhatti, R., Singh, A., & Singh Ishar, M. (2010). Ameliorative effect of the cinnamon oil from Cinnamomum zeylanicum upon early stage diabetic nephropathy. Planta Medica, 76(05), 412–417. https://doi.org/10.1055/s-0029-1186237
National Center for Complementary and Integrative Health. (n.d.). Complementary, alternative, or integrative health: What's in a name? Retrieved January 28, 2024, from https://www.nccih.nih.gov/health/complementary-alternative-or-integrative-health-whats-in-a-name
Nicholas, S. B., Kalantar-Zadeh, K., & Norris, K. C. (2015). Socioeconomic disparities in chronic kidney disease. Advances in Chronic Kidney Disease, 22(1), 6–15. https://linkinghub.elsevier.com/retrieve/pii/S1548559514001086
Nie, F., Yang, Q., Deng, K., Sun, X., Dong, J., & Li, Z. (2015). Acupuncture-moxibustion for chronic allograft nephropathy: a randomized controlled trial. Zhongguo Zhen Jiu, 35(11). https://pubmed.ncbi.nlm.nih.gov/26939320/
Papagiannopoulos, D., Holst, D., Bechis, S. K., & Sur, R. L. (2018). A homeopathic alternative to potassium citrate in patients with recurrent nephrolithiasis. Urology, 119, 35–38. https://pubmed.ncbi.nlm.nih.gov/29522867/
Peicheng, S., Xuejun, Y., & Liqun, H. (2016). Effect of Astragali and Angelica particle on proteinuria in Chinese patients with primary glomerulonephritis. Journal of Traditional Chinese Medicine, 36(3), 299–306. https://doi.org/10.1016/s0254-6272(16)30041-3
Popat, A., Shear, N. H., Malkiewicz, I., Stewart, M. J., Steenkamp, V., Thomson, S., & Neuman, M. G. (2001). The toxicity of Callilepis laureola, a South African traditional herbal medicine. Clinical Biochemistry, 34(3), 229–236. https://linkinghub.elsevier.com/retrieve/pii/S0009912001002193
Rodríguez Lara, H., Espinosa Aguilar, A., & Elers Mastrapa, Y. (2022). Las terapias alternativas como solución al cuidado de problemas crónicos de salud. Revista Cubana de Enfermería, 38(2). http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-03192022000200016&lng=es
Sánchez-Cedillo, A., Cruz-Santiago, J., Mariño-Rojas, F. B., Torres-González, J. L., Medina-García, I. A., García-Márquez, J. C., Durán-Álvarez, J. C., López-Ugalde, M. V., Ramos-Guerrero, C. A., & Sánchez-Ramírez, O. (2020). Carga de la enfermedad: insuficiencia renal, diálisis-hemodiálisis y trasplante renal en México. Costo de la enfermedad. Revista Mexicana de Trasplantes, 9(1), 15-25. https://doi.org/10.35366/94025
Secretaría de Salud. (n.d.). Enfermedad renal en México: prevención, promoción, atención y seguimiento. Retrieved January 27, 2024, from https://www.gob.mx/salud/prensa/119-enfermedad-renal-en-mexico-prevencion-promocion-atencion-y-seguimiento?idiom=es
Shamsuddin, N., Karuppannan, M., Hafiz Wan Md Adnan, W. A., Farooqui, M., & Gnanasan, S. (2019). Pattern of complementary and alternative medicine (CAM) use among patients with chronic kidney disease. Complementary Therapies in Clinical Practice, 37, 86–92. https://linkinghub.elsevier.com/retrieve/pii/S1744388118306042
Stournaras, E. (2015). Herbal medicine-related hepatotoxicity. World Journal of Hepatology, 7(19), 2189. https://www.wjgnet.com/1948-5182/full/v7/i19/2189.htm
Taghizadeh, M., Soleimani, A., Bahmani, F., Moravveji, A., Asadi, A., Amirani, E., Momeni, B., Kolahdooz, F., & Asemi, Z. (2017). Metabolic response to mulberry extract supplementation in patients with diabetic nephropathy: A randomized controlled trial. Iranian Journal of Kidney Diseases, 11(6). https://pubmed.ncbi.nlm.nih.gov/29190604/
Tello-Ortega, K. E., Hernández-Santiago, E., & Rodríguez-Ortíz, G. (2020). Medicina alternativa complementaria en el tratamiento de enfermedades crónicas en el sur de Oaxaca, México. CIENCIA ergo-sum, Revista Científica Multidisciplinaria de Prospectiva, 27(2), 87. https://www.redalyc.org/articulo.oa?id=10462656007
Teruel, J. L., Burguera Vion, V., Gomis Couto, A., Rivera Gorrín, M., Fernández-Lucas, M., Rodríguez Mendiola, N., Quereda, C., Ortuño, J., & Jiménez Álvaro, S. (2015). Elección de tratamiento conservador en la enfermedad renal crónica. Nefrología, 35(3), 273–279. https://linkinghub.elsevier.com/retrieve/pii/S0211699515000090
Vaishnav, B. S., Hirapara, J. J., & Shah, M. K. (2022). Study of effect of guided meditation on quality of life in patients of end stage renal disease (ESRD) on maintenance hemodialysis – a randomised controlled trial. BMC Complementary Medicine and Therapies, 22(1). https://pubmed.ncbi.nlm.nih.gov/36085065/
Villarreal-Ríos, E., Palacios-Mateos, A. F., Galicia-Rodríguez, L., Vargas-Daza, E. R., Baca-Moreno, C., & Lugo-Rodríguez, A. (2020). Costo institucional del paciente con enfermedad renal crónica manejada con hemodiálisis. Revista Médica del Instituto Mexicano del Seguro Social, 58(6), 698-708. https://www.redalyc.org/articulo.oa?id=457769357009
Wang, K.-X., Liang, F.-X., Chen, S., Qu, H.-Y., Gao, F., Shu, Q., Li, M., & Hu, H.-B. (2022). Effect of electroacupuncture of "Biao-Ben" acupoints on renal function and hemorheology and eNOS level in patients with early diabetic nephropathy. Acupuncture Research, 47(1), 46-52. https://doi.org/10.13702/j.1000-0607.20210036
Weir, M. A., Walsh, M., Cuerden, M. S., Sontrop, J. M., Urquhart, B. L., Lim, Y. J., Thiessen-Philbrook, H., Fraser, L.-A., Spence, J. D., Stitt, L., House, A. A., & Garg, A. X. (2023). The effect of micro-particle curcumin on chronic kidney disease progression: the MPAC-CKD randomized clinical trial. Nephrology Dialysis Transplantation, 38(10), 2192–2200. https://pubmed.ncbi.nlm.nih.gov/36849161/
Xu, X., Zhu, R., Ying, J., Zhao, M., Wu, X., Cao, G., Li, J., Wang, L., & Shi, Z. (2020). Nephrotoxicity of herbal medicine and its prevention. Frontiers in Pharmacology, 11. https://doi.org/10.3389/fphar.2020.569551
Yeam, C. T., Yo, T. E., Tan, Y. L. C., Liew, A., & Seng, J. J. B. (2021). Complementary and alternative medicine therapies for uremic pruritus – A systematic review of randomized controlled trials. Complementary Therapies in Medicine, 56, Article 102609. https://linkinghub.elsevier.com/retrieve/pii/S0965229920318768
Yu, J.-S., Ho, C.-H., Wang, H.-Y., Chen, Y.-H., & Hsieh, C.-L. (2017). Acupuncture on renal function in patients with chronic kidney disease: A single-blinded, randomized, preliminary controlled study. The Journal of Alternative and Complementary Medicine, 23(8), 624–631. https://pubmed.ncbi.nlm.nih.gov/28422526/
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