Meningitis due to candida albicans in premature infants in the neonatology service: case report

Authors

DOI:

https://doi.org/10.24054/cbs.v2i2.2931

Keywords:

meningitis fungal, neonatology, seizures, cerebrospinal fluid, infectious disease medicine

Abstract

Candida infections in the neonatal population are frequent considering the age of the patient and additional risk factors, but meningitis caused by the same germ is infrequent due to the limitation of early diagnosis and false negatives in the cerebrospinal fluid. We present two cases of patients in the Neonatology area who start with hemodynamic deterioration and convulsive crisis, so an approach is made, initially due to the characteristics of the cerebrospinal fluid in management with antibiotic scheme, but when a positive culture for Candida albicans is reported, specific management is indicated, both with progressive clinical deterioration and multiple complications, so they finally die.

References

Inder TE, Volpe JJ, du Plessis AJ, de Vries LS, Perlman JM, Darras BT, et al. Volpe’s neurology of the newborn. 6a ed. Filadelfia, PA, Estados Unidos de América: Elsevier - Health Sciences Division; 2017

James Donald Cherry, Harrison GJ, Kaplan SL, Hotez PJ, Steinbach WJ. Feigin and Cherry’s Textbook of Pediatric Infectious Diseases. 2019.

McDonnell M. Fungal infections in the newborn. Seminars in Neonatology. 1996 May;1(2):141–5.

Guillén-Pinto D, Málaga-Espinoza B, Ye-Tay J, Rospigliosi-López ML, Montenegro-Rivera A, Rivas M, et al. Neonatal meningitis: a multicenter study in Lima, Peru. Revista Peruana De Medicina Experimental Y Salud Publica [Internet]. 2020 Apr 1 [cited 2022 May 25];37(2):210–9. Available from: https://pubmed.ncbi.nlm.nih.gov/32876208/

Ipek, MS. Neonatal bacterial meningitis. En: Chubarova AI, editor. Neonatal medicine [Internet]. London: IntechOpen; 2019. Disponible Perlman J. Neurology neonatology questions and controversies. 2.ª ed. Pennsylvania: Elsevier; 2012.

Pappas PG, Kauffman CA, Andes DR, Clancy CJ, Marr KA, Ostrosky-Zeichner L, et al. Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America [Internet]. 2016;62(4): e1-50. Available from: https://www.ncbi.nlm.nih.gov/pubmed/26679628

Published

2024-05-16

How to Cite

Rincón Ardila, O. I., Manríquez Flores, M. F., López Arteaga, V. Z., Corral Rico, C., & Romero Samaniego, E. (2024). Meningitis due to candida albicans in premature infants in the neonatology service: case report. Basic Health Sciencies Journal, 2(2), 91–99. https://doi.org/10.24054/cbs.v2i2.2931

Issue

Section

Case Series